Color Doppler Ultrasound Imaging Course
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Enhance your medical skills with our Doppler Ultrasound Course! Master blood flow assessment and vascular diagnosis with expert-led training, hands-on practice, and cutting-edge techniques. Enroll now to advance your career. Visit our website https://www.mediflick.com/courses/DOPPLERCON-65f09653540b9628dc5221bc
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Gate Control Theory: Tactile input via Aβ fibers inhibits pain transmission
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Tic Douloureux: Trigeminal neuralgia characterized by sudden, stabbing facial pain
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Extracranial: Muscle spasm, sinusitis, eye strain, light exposure
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Central vs. Peripheral Lesions in pain disorders
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Allama Iqbal Medical College (Best Graduate)
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Larger surface area → enhanced detection (as fine as 0.01°C)
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Common Sexual Problems in men:
Based on his daily practice, treatments and research; he says that both married and unmarried men can struggle with their sexual problems. He says that men struggle with erectile dysfunction, premature ejaculation, lack of sexual desire, culture-specific syndromes, ejaculation disorders, sexually transmitted infections, performance anxiety disorder and other sexual problems. Various factors are responsible for sexual problems and among them; physical, psychological, lifestyle, hormonal, medical conditions and emotional factors play a vital role in leading a person to sexual problems.
Ayurvedic Treatment for Overall Male Sexual Problems:
Dr. Sunil Dubey says that Ayurveda has infallible solutions to deal with all sexual problems of men. The approach of Ayurveda focuses on balancing the doshas in the body, which are the cause of sexual disorders. It has a natural system to cure problems, which is the basis of all medicines. He provides his comprehensive treatment to each and every sexual patient with the help of Ayurveda.
First, he identifies the underlying medical conditions (diabetes, cardiac problems, kidney disease and chronic illness) that play a vital role in this sexual problem. He also helps in identifying psychological factors (stress, depression, anxiety, relationship issues and emotional factors) that indirectly affect sexual health. Providing a holistic approach of treatment, he provides clinically proven Ayurvedic medicine, herbal remedies, quality-proven Ayurvedic Bhasma and vital guidance of sexual wellness.
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Technology
For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did.
While technology has helped us keep in touch with friends and family in faraway places, it appears to have degraded our ability to connect in person. Staying connected online is a double-edged sword since the same news feed that brings us pictures of the grandkids and fluffy kittens also feeds us news about the wars in Israel and Ukraine, the dysfunction in Washington, the latest mass shooting and the climate crisis.
Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad.
Age and Gender
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Race Affects Attitudes
As seen in previous research conducted by ThinkNow, Asian Americans lag other groups when it comes to awareness of mental health issues. Twenty-four percent of Asian Americans believe that having a mental health issue is a sign of weakness compared to the 16% average for all groups. Asians are also considerably less likely to be aware of mental health services in their communities (42% vs. 55%) and most likely to seek out information on social media (51% vs. 35%).
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HIV AIDS for university students studying
HIV AIDS for university students studyingarthurtheophilus56 duce their risk of acquiring HIV.**
* **Highly effective when taken consistently.**
* **Requires regular HIV testing and medical monitoring.**
• **Post-Exposure Prophylaxis (PEP):**
* **Antiretroviral medications taken after a potential exposure to HIV to prevent infection.**
* **Must be started within 72 hours of exposure.**
* **Typically involves a 28-day course of ART.**
• **Harm Reduction Strategies:**
* **Needle Exchange Programs:** Provide clean needles and syringes to intravenous drug users to reduce the risk of sharing needles and transmitting HIV.
* **Opioid Substitution Therapy:** Using medications such as methadone or buprenorphine to treat opioid addiction.
• **Education and Awareness:**
* **Providing accurate information about HIV transmission, prevention, and treatment.**
* **Addressing stigma and discrimination associated with HIV.**
**VIII. Global Impact of HIV/AIDS**
HIV/AIDS has had a profound impact on global health and development.
• **Prevalence:** An estimated 38.4 million people worldwide were living with HIV in 2021.
• **New Infections:** Approximately 1.5 million new HIV infections occurred in 2021.
• **Deaths:** 650,000 people died from AIDS-related illnesses in 2021.
• **Regional Differences:** The burden of HIV/AIDS is disproportionately high in sub-Saharan Africa.
• **Impact on Life Expectancy:** HIV/AIDS has significantly reduced life expectancy in many countries.
• **Economic Impact:** HIV/AIDS has had a negative impact on economic development, particularly in countries with high prevalence rates.
• **Social Impact:** HIV/AIDS has led to stigma, discrimination, and social isolation for affected individuals and communities.
**IX. Ongoing Research and Future Directions**
Research continues to play a vital role in the fight against HIV/AIDS.
• **Cure Research:** Scientists are working to develop a cure for HIV infection, which could involve eliminating the virus from the body or achieving long-term remission without the need for ART.
• **Vaccine Development:** Efforts are underway to develop a safe and effective HIV vaccine that could prevent new infections.
• **Improved Treatment Strategies:** Researchers are developing new antiretroviral drugs that are more effective, easier to take, and have fewer side effects.
• **Prevention Strategies:** Scientists are exploring new prevention strategies, such as long-acting injectable PrEP and broadly neutralizing antibodies.
• **Understanding HIV Reservoirs:** Research is focused on understanding HIV reservoirs, which are cells in the body where HIV can hide and persist even during ART.
• **Addressing Co-morbidities:** Research is exploring how HIV infection affects other health conditions, such as cardiovascular disease, cancer, and neurological disorders.
**X. Conclusion**
HIV/AIDS remains a significant global health challenge, but significant progress has been made in recent decad
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Esophageal Cancer: Artificial Intelligence, Synergetics, Complex System Analy...Oleg Kshivets We analyzed data of 568 consecutive ECP (age=56.7±9 years; tumor size=5.9±3.5 cm) radically operated (R0) and monitored in 1975-2025 (m=424, f=144; esophagogastrectomies (EG) Garlock=290, EG Lewis=278, combined EG with resection of pancreas, liver, diaphragm, aorta, VCS, colon transversum, lung, trachea, pericardium, splenectomy=174; adenocarcinoma=326, squamous=232, mix=10; T1=133, T2=121, T3=186, T4=128; N0=288, N1=71, N2=209; G1=161, G2=143, G3=264; early EC=114, invasive=454; only surgery=431, adjuvant chemoimmunoradiotherapy-AT=137: 5-FU+thymalin/taktivin+radiotherapy 45-50Gy). Multivariate Cox modeling, clustering, SEPATH, Monte Carlo, bootstrap and neural networks computing were used to determine any significant dependence.
RESULTS: Overall life span (LS) was 1906.3±2278.4 days and cumulative 5-year survival (5YS) reached 53%, 10 years – 46.4%, 20 years – 33.4%, 30 years – 27.5%. 194 ECP lived more than 5 years (LS=4300.8±2503.5 days), 105 ECP – more than 10 years (LS=5860.8±2469.2 days). 232 ECP died because of EC (LS=628.8±321.8 days). AT significantly improved 5YS (60.3% vs. 43.1%) (P=0.007 by log-rank test). 5YS of ECP of upper/3 was significantly better than others (65.3% vs.50.3%) (P=0.003). Cox modeling displayed that 5YS of ECP significantly depended on: phase transition (PT) N0—N12 in terms of synergetics, blood cell subpopulation, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), EC cell dynamics, T, G, histology, age, localization, prothrombin index, coagulation time, residual nitrogen, chlorides (P=0.000-0.047). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and healthy cells/CC (rank=1), erythrocytes/CC (2), PT N0—N12 (3), PT early-invasive EC (4), thrombocytes/CC (5); segmented neutrophils/CC (6), lymphocytes/CC (7), eosinophils/CC (8), stick neutrophils/CC (9), leucocytes/CC (10), monocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5-year survival of ECP after radical procedures significantly depended on: 1) PT “early-invasive cancer”; 2) PT N0--N12; 3) Cell Ratio Factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) EC cell dynamics; 9) EC characteristics; 10) tumor localization; 11) anthropometric data; 12) surgery type. Optimal diagnosis and treatment strategies for EC are: 1) screening and early detection of EC; 2) availability of sufficient quantity of very experienced thoracoabdominal surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for ECP with unfavorable prognosis.
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Visceral pleura: covers the surface of the lungs.
Parietal pleura: lines the chest wall, diaphragm, and mediastinum.
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PLEURAL EFFUSION By Dr. Kritika Somani..
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Analgesia system & Abnormalities of Pain_AntiCopy.pdf
Analgesia system & Abnormalities of Pain_AntiCopy.pdfMedicoseAcademics This comprehensive lecture by Dr. Faiza (MBBS – Best Graduate, AIMC Lahore | FCPS Physiology | ICMT, CHPE, DHPE – STMU | MPH – GC University Faisalabad | MBA – Virtual University of Pakistan) provides an expert-level overview of the central analgesia system, pain modulation mechanisms, and various clinical abnormalities of pain.
Designed for undergraduate and postgraduate medical learners, this session integrates neurophysiology, pharmacology, and clinical neurology to explain how the body perceives, modulates, and at times misinterprets pain.
🧠 Key Learning Objectives:
Understand the central pain modulation system and its neural architecture.
Explore the role of endogenous and exogenous opioids in analgesia.
Analyze the physiological basis of non-pharmacological pain relief (massage, acupuncture, liniments, electrical stimulation).
Enumerate and explain abnormal pain conditions such as hyperalgesia, allodynia, shingles, trigeminal neuralgia, and different types of headaches.
Interpret the pathophysiology of migraines including vascular and cortical spreading depression theories.
🔬 Lecture Highlights:
✅ Central Analgesia System:
Neural pathways: Periaqueductal gray, Raphe magnus nucleus, spinal dorsal horn
Neurochemicals involved: Enkephalins, Serotonin
Gate Control Theory: Tactile input via Aβ fibers inhibits pain transmission
✅ Pain Suppression Mechanisms:
Massage & Rubbing: Local tactile inhibition via Aβ fibers
Acupuncture & Liniments: Dual role in stimulating pain gating and central analgesia
Electrical Stimulation: From surface electrodes to stereotactic thalamic implants
Patient-controlled neuromodulation: Tailoring stimulation for chronic pain
✅ Abnormalities of Pain:
Hyperalgesia: Heightened sensitivity to painful stimuli (primary and secondary)
Allodynia: Pain perception from non-painful stimuli
Herpes Zoster: Segmental dermatomal pain from dorsal root ganglion infection
Tic Douloureux: Trigeminal neuralgia characterized by sudden, stabbing facial pain
✅ Headache Pathophysiology:
Intracranial: Meningitis, low CSF pressure, migraines, alcohol
Extracranial: Muscle spasm, sinusitis, eye strain, light exposure
Migraine Mechanisms: Vascular spasm, cortical depression, serotonin imbalance, and familial genetics
✅ Clinical Correlation:
Brown-Séquard Syndrome: Sensory and motor dissociation explained by hemisection
Central vs. Peripheral Lesions in pain disorders
👨⚕️ Ideal for:
MBBS, BDS, and Allied Health Students
FCPS/MD/MS Physiology Trainees
Residents in Neurology, Anesthesia, and Internal Medicine
Physiology educators and academic examiners
Candidates preparing for USMLE, PLAB, FCPS, MDCAT, or Step 1
Presented by:
Dr. Faiza
Assistant Professor of Physiology
FCPS Physiology | CHPE | DHPE | MPH | MBA
Allama Iqbal Medical College (Best Graduate)
Physiology of Pain and thermal sensations
Physiology of Pain and thermal sensationsMedicoseAcademics This in-depth lecture by Dr. Faiza, Assistant Professor of Physiology and a distinguished graduate of Allama Iqbal Medical College (Best Graduate, MBBS 2017), offers a thorough exploration of the neurophysiology of pain and temperature sensation. With advanced qualifications including FCPS in Physiology, CHPE, DHPE (STMU), MPH (GC University), and MBA (Virtual University), Dr. Faiza brings both clinical insight and pedagogical clarity to complex sensory concepts.
🔍 What You’ll Learn in This Lecture:
I. Pain Sensation:
Types of Pain: Acute (fast, sharp) vs. Chronic (slow, burning)
Nociceptors: Distribution, types (mechanical, thermal, chemical, polymodal), and functional characteristics
Pain Receptor Activation:
TRPV1 (heat, vanilloids), TRPA1 (cold, mechanical)
ASICs (acid-sensing ion channels)
Bradykinin, prostaglandin, and purinergic receptors
Mechanism of Pain Transmission:
Rate of tissue damage as a key determinant
Pain stimuli: mechanical spasm, thermal injury (>45°C), ischemia-induced chemical pain
Dual Pain Pathways:
Neospinothalamic Tract (Fast pain): Aδ fibers, glutamate neurotransmission, thalamic projection
Paleospinothalamic Tract (Slow pain): C fibers, substance P and glutamate, brainstem involvement
II. Central Processing of Pain:
Major relay centers: Thalamus, Reticular formation, Periaqueductal gray, Mesencephalon
Functional roles of cerebral cortex vs. brainstem in pain perception
Effects of anterolateral cordotomy and thalamic ablation
III. Thermal Sensation:
Perception spectrum: Freezing cold → Burning hot
Receptor Types:
Cold Receptors: Aδ and C fibers; peak at ~24°C
Warm Receptors: Type C fibers; active from ~30–49°C
Thermal Pain Receptors: Activated at extremes; overlap with nociceptors
Mechanism of Thermal Transduction:
Based on metabolic rate modulation and intracellular chemical reaction dynamics
Adaptation Properties:
Rapid initial decline with ongoing stimulation
Importance of dynamic change (falling/rising temperature) over static input
Spatial Summation:
Larger surface area → enhanced detection (as fine as 0.01°C)
Small area → requires larger temperature shifts
🧠 Clinical Relevance:
Phantom limb pain: central sensitization, cortical plasticity
Mechanistic differences between local anesthesia and opioid response
Importance of understanding dual pain pathways in anesthesia, pain management, and neurosurgery
🎯 Ideal For:
MBBS, BDS, and Nursing students
Postgraduate Physiology and FCPS candidates
Medical educators and examiners
Professionals preparing for PLAB, USMLE, and other licensing exams
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Evaluation Of Cosmetic Products
Indian Standard Specification
Bureau Indian Standards.
Comprehensive Analysis Of Raw Materials And Finished Products
PRESENTED BY-DHANASHREE G. KOLHEKAR (2nd SEM), M.PHARMACY (PHARMACEUTICAL ANALYSIS)
Introduction
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Common Male Sexual Problems | Best Sexologist in Patna, Bihar | Dr. Sunil DubeySexologist Dr. Sunil Dubey - Dubey Clinic Hello friends, welcome to Dubey Clinic!
If you are a male and looking for a sexologist doctor for personal treatment or medicine then this information is helpful for you. As we know a sexologist doctor is a specialist in his medical faculty to treat patients who are suffering from any kind of sexual problems. He is a specialist in the study of sexuality, sexology, sexual dysfunction, sexual desire, behavior, gender-identity, anatomy and reproductive health issues. He practices in a clinic or hospital to provide his treatment and medicine privileges.
World renowned Ayurvedacharya Dr. Sunil Dubey is the best sexologist doctor in Patna, Bihar who provides his comprehensive treatment for married and unmarried people at Dubey Clinic. He is a highly qualified Ayurvedic doctor who is an expert in sexology medicine and therapy. In his treatment, he uses the entire branches of Ayurveda (modern, traditional, specific and others) to treat his sexual patients. He is also a successful researcher in this Ayurvedic sexologist profession who has successfully done his research on various sexual diseases in men and women.
Common Sexual Problems in men:
Based on his daily practice, treatments and research; he says that both married and unmarried men can struggle with their sexual problems. He says that men struggle with erectile dysfunction, premature ejaculation, lack of sexual desire, culture-specific syndromes, ejaculation disorders, sexually transmitted infections, performance anxiety disorder and other sexual problems. Various factors are responsible for sexual problems and among them; physical, psychological, lifestyle, hormonal, medical conditions and emotional factors play a vital role in leading a person to sexual problems.
Ayurvedic Treatment for Overall Male Sexual Problems:
Dr. Sunil Dubey says that Ayurveda has infallible solutions to deal with all sexual problems of men. The approach of Ayurveda focuses on balancing the doshas in the body, which are the cause of sexual disorders. It has a natural system to cure problems, which is the basis of all medicines. He provides his comprehensive treatment to each and every sexual patient with the help of Ayurveda.
First, he identifies the underlying medical conditions (diabetes, cardiac problems, kidney disease and chronic illness) that play a vital role in this sexual problem. He also helps in identifying psychological factors (stress, depression, anxiety, relationship issues and emotional factors) that indirectly affect sexual health. Providing a holistic approach of treatment, he provides clinically proven Ayurvedic medicine, herbal remedies, quality-proven Ayurvedic Bhasma and vital guidance of sexual wellness.
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- Developing a personal brand through a website and social media presence.
- Networking through events, communities, and finding a mentor.
- Practicing interviews through mock interviews and whiteboarding coding questions.
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2. There are many possible user intents beyond just transactional, navigational and informational. Identifying intent shifts is important during core updates. Sites may need to optimize for new intents through different content types and sections.
3. Responding effectively to core updates requires analyzing "before and after" data to understand changes, identifying new intents or page types, and ensuring content matches appropriate intents across video, images, knowledge graphs and more.
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Introduction to Data Science
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Time Management & Productivity - Best Practices
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We’ve stripped back project management processes to the
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the vital ingredients for success.
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Dr Andrew Makar, Tactical Project Management
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• Learn how to use ChatGPT to add AI power to your testing and test automation
• Understand the limitations of the technology and where human expertise is crucial
• Gain insight into different AI-based tools
• Adopt AI-based tools to stay relevant and optimize work for developers and testers
* ChatGPT and OpenAI belong to OpenAI, L.L.C.
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Color Doppler Ultrasound Imaging Course
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